Depression Series: My Antidepressant Doesn’t Work. What Can My Psychiatrist Do? (Part 2)

by: Michael G. Rayel, MD
Maria has been increasingly depressed for the past few years. She has tried at least four newer antidepressants but so far, she doesn’t seem to respond. Unable to work, she’s now feeling helpless and hopeless. Likewise, her family is discouraged. Frustrated and baffled by Maria’s lack of progress, the family doctor [...]

Depression Series: Why Don’t I Respond to Medications? (Part 1)

by: Michael G. Rayel, MD
Maria has been feeling depressed for at least two and a half years. About three years ago, her husband of 20 years left her for another woman. Devastated, she became despondent and tearful almost daily.
Eventually, her depression got worse associated with inability to function. Her appetite, energy, concentration, and sleep became [...]